tert-Butyl 4-(4-bromophenyl)piperazine-1-carboxylate

tert-Butyl 4-(4-bromophenyl)piperazine-1-carboxylate - Names and Identifiers

Name	4-(4-BROMO-PHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
Synonyms	1-Boc-4-(4-Bromophenyl)piperazine 4-(4-Boc-Piperazino)-1-bromobenzene t-Butyl 4-(4-Bromophenyl)piperazine-1-carboxylate 1-tert-Butoxycarbonyl-4-(4-broMophenyl)piperazine tert-Butyl 4-(4-bromophenyl)piperazine-1-carboxylate 4-(4-BROMO-PHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1-Piperazinecarboxylic acid, 4-(4-broMophenyl)-, 1,1-diMethylethyl ester tert-Butyl 4-(4-bromophenyl)piperazine-1-carboxylate, 1-(4-Bromophenyl)-4-(tert-butoxycarbonyl)piperazine
CAS	352437-09-3

tert-Butyl 4-(4-bromophenyl)piperazine-1-carboxylate - Physico-chemical Properties

Molecular Formula	C15H21BrN2O2
Molar Mass	341.24
Density	1.332±0.06 g/cm3(Predicted)
Melting Point	146.3-147.5 °C
Boling Point	424.7±40.0 °C(Predicted)
pKa	2.83±0.10(Predicted)
Storage Condition	Room temperature.
Use	This product is for scientific research only and shall not be used for other purposes.

tert-Butyl 4-(4-bromophenyl)piperazine-1-carboxylate - Risk and Safety

Hazard Symbols

Xi - Irritant

tert-Butyl 4-(4-bromophenyl)piperazine-1-carboxylate - Upstream Downstream Industry

Raw Materials	1-Piperazinecarboxylic acid, 4-(benzoyloxy)-, 1,1-dimethylethyl ester 4-BROMOBENZENEBORONIC ACID NEOPENTYL GLYCOL ESTER 4-Bromoaniline Di-tert-butyl dicarbonate 1-Phenylpiperazine 4-Bromophenylboronic acid Bis(2-chloroethyl)amine hydrochloride 1-Bromo-4-iodobenzene 1,4-Dibromobenzene tert-Butyl 1-piperazinecarboxylate
Downstream Products	1-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-piperazine 1-(4-BROMOPHENYL)PIPERAZINE

tert-Butyl 4-(4-bromophenyl)piperazine-1-carboxylate - Introduction

4-(4-BROMO-PHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is an organic compound with the chemical formula C19H25BrN2O2.

its nature:
Appearance: White to yellowish crystals
Melting point: About 70-73 ° C
Solubility: Soluble in some organic solvents such as ether and dichloromethane, slightly soluble in water

Use:
4-(4-BROMO-PHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is a common organic synthesis intermediate, commonly used in the field of medicine and pesticide. It can be used to synthesize compounds with antitumor, antiviral, antifungal and antibacterial activity. It can also be used as a protecting group for biologically active molecules.

Method:
Generally, 4-(4-BROMO-PHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER can be prepared by the following steps:
First, 4-bromoacetophenone is reacted with piperazine to produce 4-(4-bromophenyl) piperazine. 4-(4-bromophenyl) piperazine is then reacted with tert-butyl chloroformate to give the final product, 4-(4-BROMO-PHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER.

Safety Information:
4-(4-BROMO-PHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is relatively safe under correct operation, it still needs to be used with caution. It should be kept away from fire sources and strong oxidants, and avoid contact with skin and eyes. Appropriate protective equipment such as lab gloves and goggles should be used during operation. If inhaled or ingested by mistake, seek medical attention immediately. Refer to the chemical's safety data sheet for detailed safety information and operational recommendations.

Last Update：2024-04-09 21:01:54